肠道菌群与痤疮发生的相关性分析：110例肠道菌群样本的回顾性研究

作者：王萃 张柳萦 黄卫新

来源：《中国美容医学》2018年第09期

        [摘要]目的：探讨肠道菌群是否参与痤疮的发病。方法：回顾性调查分析树兰（杭州）医院曾进行肠道菌群检测的110例患者。根据皮肤状态将其分为痤疮组和非痤疮组，并设计LND评分表对痤疮严重程度进行量化评估，运用R统计软件（t检验，皮尔逊相关性检验）进行两组间肠道6种优势细菌菌群差异分析。结果：两组肠道菌群多样性未发现显著差异，但痤疮组的乳酸菌、双歧杆菌数量均少于非痤疮组，且痤疮组的双歧杆菌与肠杆菌比值（B/E值）低于非痤疮组，差异均有统计学意义（P

        [关键词]痤疮；肠道微生态；聚合酶链式反应；回顾性

        [中图分类号]R758.73+3 [文献标志码]A [文章编号]1008-6455（2018）09-0009-04

        Correlation Analysis of Intestinal Microflora and Acne： A Retrospective Study

        on 110 Patients

        WANG Cui1，ZHANG Liu-ying2，HUANG Wei-xin2

        [1.Department of Plastic Surgery，Shulan （Hangzhou） Hospital，Hangzhou 310000，Zhejiang，China；2.Zhejiang Tongchuang Yuecheng Health Technology Co.，Ltd， Shaoxing 312000，Zhejiang，China]

        Abstract： Objective In this study， we retrospective investigate changes in intestinal microflora in patients with acne， and their role in this dermatological disorder. Methods 110 patients whose fecal flora were analyzed within a year were retrospective studied. They were classified into acne group and non-acne group. LND tool was used to assess the acne. The numbers of intestinal microflora between the two groups were statistical analyzed. Results The number of fecal lactobacillus， as well as bifidobacterium were significantly deceased in patients with acne compared with the non-acne group， and B/E （Bifidobacterium/Enterobacter） was significantly deceased in patients with acne compared with the non-acne group， the differences were statistically significant（P

肠道菌群与痤疮发生的相关性分析：110例肠道菌群样本的回顾性研究