Dietary Recommendations for Omega-3 Fatty Acids

发布时间:2011-10-27 14:48:06

Dietary Recommendations for Omega-3 Fatty Acids

Many leading authorities and nutrition and health organizations have developed specific dietary recommendations for omega-3 fatty acids for different countries around the world. We have obtained the following information to improve education on omega-3 fatty acids by providing the global perspective on their requirements and the agencies that developed the information to improve human nutrition and health.

United States

Organization (org. Type)

Target Population

Recommendation

Institute of Medicine12

(Authoritative Body)

Adult men ³ 19 yrs

ALA :1.6 g/day of which approximately 10% EPA+DHA

Adult women ³ 19 yrs

ALA: 1.1 g/day of which approximately 10% EPA+DHA

American Dietetics Association23

(Expert Scientific Organization)

General Adult Population

500mg/day long-chain PUFA intake

March of Dimes32

(Expert Scientific Organization)

Pregnant and Nursing Women

200mg DHA from fish, fortified foods or supplements

National Heart, Lung, and BloodInstitute, National CholesterolEducation Program13

(Authoritative Body)

Persons with CHD or multiple risk factors for CHD

Supported AHA recommendation to include fish as part of a CHD risk reduction diet. Higher dietary intakes of n-3 PUFAs are an option for reducing CHD risk

American Heart Association14

(Expert Scientific Organization)

All adults without CHD

Eat fish (particularly fatty fish) at least two times a week; include oils and foods rich in ALA

Patients with CHD

Consume approximately 1 g/day of EPA+DHA preferably from oily fish. EPA+DHA supplements could be considered in consultation with the physician

Patients with high triglycerides

2-4 g/day EPA+DHA as capsules under a physician's care

Dietary Guidelines Advisory Committee16

(Authoritative Body)

General adult population

Two servings of fatty fish per week, equivalent to 496mg EPA/DHA per day

Council for Responsible Nutrition17

(Expert Scientific Organization)

General adult population

Approximately 500mg/day EPA/DHA consumption from supplementation or fatty fish consumption

Executive Office of the President18

(Authoritative Body)

General population

Dietary Guidelines and Food Guide Pyramid should be revised to emphasize the benefits of increasing consumption of foods rich in omega-3 fatty acids.

Agency for Healthcare Research and Quality30

(Authoritative Body)

General adult population

Fish and fish oil supplements reduce the risk of cardiovascular disease

Global

Organization (org. Type)

Target Population

Recommendation

World Health Organization1

(Authoritative Body)

General adult population

n-3 PUFAs: 1-2% of energy/day

International Society for the Study of Fats and Lipids (ISSFAL)2

(Expert Scientific Organization)

General adult population

DHA+EPA: 0.65 g/2000kcal/day

DHA at least 0.22 g/2000kcal/day

EPA at least 0.22 g/2000kcal/day

Pregnant/nursing women

DHA: 300 mg/day

NATO Workshop on w-3 and w-6 Fatty Acids22

(Expert Scientific Organization)

General Adult Population

800mg EPA/DHA per day

World Association of Perinatal Medicine29

(Expert Scientific Organization)

Pregnant and Lactating Women

200mg DHA per day

World Gastroenterology Organization24

(Expert Scientific Organization)

General Adult Population

3-5 fish servings per week to get EPA and DHA

Australia

Organization (org. Type)

Target Population

Recommendation

National Heart Foundation of Australia3

(Expert Scientific Organization)

General adult population

500mg EPA/DHA per day, obtained through fish, fish oil supplements, or enriched foods for prevention of heart disease

Patients with documented CHD

1000mg EPA/DHA per day, obtained through fish, fish oil supplements, or enriched foods for prevention of heart disease

Patients with hypertriglyceridemia

1200mg of EPA/DHA from fish oil capsules and enriched foods as first-line therapy

Raise to 4000mg of EPA/DHA per day, as needed.

Australian & New Zealand Health Authorities (Department of Health & Ageing, National Health & Medical Research Council)28

(Authoritative Bodies)

Infants (0-12 mo)

0.5 g n-3 polyunsaturated fats/day adequate intake

Boys & Girls (1-3 yrs)

40 mg total LC n-3 (DHA+EPA+DPA)/day adequate intake

Boys & Girls (4-8 yrs)

55 mg total LC n-3 (DHA+EPA+DPA)/day adequate intake

Boys & Girls (9-13 yrs)

70 mg total LC n-3 (DHA+EPA+DPA)/day adequate intake

Boys (14-18 yrs)

125 mg total LC n-3 (DHA+EPA+DPA)/day adequate intake

Girls (14-18 yrs)

85 mg total LC n-3 (DHA+EPA+DPA)/day adequate intake

Men (19+ yrs)

160 mg total LC n-3 (DHA+EPA+DPA)/day adequate intake

Women (19+ yrs)

90 mg total LC n-3 (DHA+EPA+DPA)/day adequate intake

Pregnancy (14 -18 yrs)

110 mg total LC n-3 (DHA+EPA+DPA)/day

Pregnancy (19-50 yrs)

115 mg total LC n-3 (DHA+EPA+DPA)/day

Lactating - (14-18 yrs)

140 mg LC n-3 (DHA+EPA+DPA)/day

Lactating - (19-50 yrs)

145 mg LC n-3 (DHA+EPA+DPA)/day

Defence Science and Technology Organisation, Department of Defence34

(Authoritative Body)

Men

610mg LC n-3 (DHA+EPA+DPA)/day dietary target

Women

430mg LC n-3 (DHA+EPA+DPA)/day dietary target

Male soldiers

610mg EPA+DPA+DHA/day

Female soldiers

430mg EPA+DPA+DHA/day

Austria

Organization (org. Type)

Target Population

Recommendation

Austrian Society for Nutrition33

(Expert Scientific Organization)

General adult population

250mg LCPUFA/day for primary prevention of CVD

General adult population

0.5% of energy total n-3 PUFA intake

CHD Patients

1g LCPUFA/day for secondary prevention of CVD

Pregnant & nursing women

At least 200mg DHA/day

Belgium

Organization (org. Type)

Target Population

Recommendation

Belgian Superior Health Council20

(Authoritative Body)

Pregnant & nursing women

250mg DHA/day

General adult population

Two servings of fatty fish/week

CHD Patients

1g EPA/DHA per day from capsules

Canada

Organization (org. Type)

Target Population

Recommendation

Health and Welfare, Canada4

(Authoritative Body)

General adult population

1.1-1.6 g/day total n-3 PUFA (ALA, EPA, DHA)

Dieticians of Canada23

(Expert Scientific Organization)

General adult population

500mg long-chain PUFA/day

Europe

Organization (org. Type)

Target Population

Recommendation

Expert Workshop of the European Academy of Nutritional Sciences5

(Expert Scientific Organization)

General Adult Population

People who do not eat fish should consider consuming marine n-3 PUFA equivalent to the amount obtained from fatty fish, namely 200 mg EPA + DHA daily

European Food Safety Agency25

(Authoritative Body)

General Adult Population

250mg EPA+DHA per day

Pregnant & Lactating Women

100-200mg DHA per day in addition to normal adult requirements

Children 7-24 months

100mg DHA per day

Children 2-18 years

250mg EPA+DHA per day

The PeriLip and EARNEST projects of the European Commission31

(Expert Scientific Organization)

Pregnant & Lactating Women

200mg DHA/day

France

Organization (org. Type)

Target Population

Recommendation

AFFSA21

(Authoritative Body)

General Adult Population

General Nutrition

o 250mg DHA per day (previously 120mg)

o 250mg EPA per day

o 500mg EPA+DHA per day

500mg per day for metabolic disease risk reduction

500-750mg per day for cardiovascular disease risk reduction

500mg per day for breast and colon cancer risk reduction

>200-300mg per day for neuropsychiatric risk reduction

500mg per day for AMD risk reduction

Infants (0-6 months)

0.32% of fats from DHA

EPA

Infants & Toddlers (6 months to 3 years)

70mg DHA per day

Children (3-9 years)

125mg DHA per day

250mg EPA+DHA per day

Adolescents (9 to 18 years)

250mg DHA per day

500mg EPA+DHA per day

Pregnant & Nursing Women

250mg DHA per day

500mg EPA+DHA per day

Germany

Organization (org. Type)

Target Population

Recommendation

German Society for Nutrition33

(Expert Scientific Organization)

General adult population

250mg LCPUFA / day for primary prevention of CVD

General adult population

0.5% of energy total n-3 PUFA intake

CHD Patients

1g LCPUFA/day for secondary prevention of CVD

Pregnant & nursing women

At least 200mg DHA/day

Japan

Organization (org. Type)

Target Population

Recommendation

Ministry of Health, Labor andWelfare

(Authoritative Body)

General adult population6

n-6:n-3 PUFAs: 4:1

Infants (0-5 months) - boys and girls26

0.9g total omega-3 per day

Infants (6-11 months)- boys and girls26

1.0g total omega-3 per day

Toddlers (1-2 years) - Boys26

1.1g total omega-3 per day

Toddlers (1-2 years) - Girls26

1.0g total omega-3 per day

Children (3-5 years) - Boys and Girls26

1.5g total omega-3 per day

Children (6-7 years) - Boys and Girls26

1.6g total omega-3 per day

Children (8-9 years) - Boys26

1.9g total omega-3 per day

Children (8-9 years) - Girls26

2.0g total omega-3 per day

Children (10-11 years) - Boys and Girls26

2.1g total omega-3 per day

Children (12-14 years) - Boys26

2.6g total omega-3 per day

Children (12-14 years) - Girls26

2.1g total omega-3 per day

Children (15-17 years) - Boys26

2.8g total omega-3 per day

Children (15-17 years) - Girls26

2.3g total omega-3 per day

Adults (18-49 years) - Men26

2.6g total omega-3 per day

Adults (18-49 years) - Women26

2.2g total omega-3 per day

Adults (50-69 years) - Men26

2.9g total omega-3 per day

Adults (50-69 years) - Women26

2.5g total omega-3 per day

Adults (Over 70 years) - Men26

2.2g total omega-3 per day

Adults (Over 70 years) - Women26

2.0g total omega-3 per day

Pregnant Women26

2.1g total omega-3 per day

Nursing Women26

2.4g total omega-3 per day

Netherlands

Organization (org. Type)

Target Population

Recommendation

Health Council of the Netherlands

(Authoritative Body)

Children 0-5 months

Total n-3 PUFAs: 80 mg/kg per day

DHA: 20 mg/kg per day

Adults

Total n-3 PUFAs: 1% of energy7

DHA: 150-200 mg per day7

n-3 fatty acids from fish: 450mg per day27

Scandinavia

Organization (org. Type)

Target Population

Recommendation

Nordic Council of Ministers8

(Authoritative Body)

Adults and children over 3 yrs

EPA+DHA: 450mg/day

Total n-3 PUFAS: 1.0% of energy/day

Switzerland

Organization (org. Type)

Target Population

Recommendation

Swiss Society for Nutrition Research / Swiss Nutrition Association33

(Expert Scientific Organization)

General adult population

250mg LCPUFA/day for primary prevention of CVD

General adult population

0.5% of energy total n-3 PUFA intake

CHD Patients

1g LCPUFA/day for secondary prevention of CVD

Pregnant & nursing women

At least 200mg DHA/day

United Kingdom

Organization (org. Type)

Target Population

Recommendation

British Nutrition Foundation9

(Expert Scientific Organization)

Adults, 19-50 yrs

one to two portions of oil-rich fish per week, which will provide around 2-3g of the very long chain n-3 fatty acids

weekly intake of 1.5g of EPA + DHA

Committee on the Medical Aspects of Food and Nutrition Policy (COMA)10

(Authoritative Body)

Adults

at least two portions of fish, of which one should be oily

weekly n-3 PUFAs: > 0.2 g/day

Scientific Advisory Committee on Nutrition11

(Authoritative Body)

Adults

weekly n-3 PUFAs @ 0.2 g/day

References

1. World Health Organization. Diet, Nutrition and the Prevention of Chronic Diseases. Technical report series 916.

2. Simopoulos AP, Leaf A, Salem N Jr. Workshop statement on the essentiality of and recommended dietary intakes for Omega-6 and Omega-3 fatty acids. Prostaglandins Leukot Essent Fatty Acids. 2000 Sep;63(3):119-121.

3. National Heart Foundation of Australia. Position statement on Fish, fish oils, n-3 polyunsaturated fattyacids and cardiovascular health. Presented at AIFST conference July 2008.

4. Health and Welfare Canada. Nutrition Recommendations: The Report of the Scientific Review Committee. 1990. Ottawa, Ontario.

5. de Deckere EA, Korver O, Verschuren PM, Katan MB. Health aspects of fish and n-3 polyunsaturated fatty acids from plant and marine origin. Eur J Clin Nutr 1998 Oct;52(10):749-753.

6. Ministry of Health and Welfare, Japan. Recommended dietary allowances for Japanese, 6th edition. Tokyo: Daiichi-Shuppan Co, 1999.

7. Health Council of the Netherlands. Dietary reference intakes: energy, proteins, fats, and digestible carbohydrates. The Hague. Health Council of the Netherlands, 2001; publication no. 2001/19 (in Dutch, with a summary and table in English).

8. NNR (Nordic Nutrition Recommendations), 2004. Integrating nutrition and physical activity. Nord 2004:13. Nordic Council of Ministers, Copenhagen.

9. British Nutrition Foundation Conference held on 1 December 1999 to draw attention to the briefing paper on 'n-3 Fatty acids and Health'

10. Department of Health. Nutritional Aspects of Cardiovascular Disease. Report on Health and Social Subjects. No 46. London: HMSO 1994.

11. Scientific Advisory Committee on Nutrition. Advice on fish consumption: benefits and risks 2004.

12. Institute of Medicine. Dietary Reference Intakes for Energy, Carbohydrate, Fiber, Fat, Fatty acids, Cholesterol, Protein, and Amino Acids. 2002. National Academy of Sciences, Washington, DC.

13. National Institutes of Health. National Heart, Lung, and Blood Institute. Third Report of the National Cholesterol Education Program Expert Panel on Detection, Evaluation, and Treatment of High Blood Cholesterol in Adults (Adult Treatment Panel III). 2001. NIH Publication Number 01-3670. Washington, DC.

14. AHA Scientific Statement: Fish Consumption, Fish Oil, Omega-3 Fatty Acids and Cardiovascular Disease, #71-0241 Circulation. 2002;106: 2747-2757.

15. EFSA. Scientific Opinion of the Panel on Dietetic products, Nutrition and Allergies on a request from European Commission related to labelling reference intake values for n-3 and n-6 polyunsaturated fatty acids. The EFSA Journal (2009) 1176, 1-11.

16. Dietary Guidelines Advisory Committee Report, Part D: Science Base, Section 4: Fats - EPA, DHA and fish. 2005.

17. Council for Responsible Nutrition. White Paper. Long Chain Omega-3 Fatty Acids in Human Health. Heart Health: The Role of EPA, DHA and ALA. 2005

18. Executive Office of the President. Office of Management and Budget, Washington, D.C.. May, 2003

19. Department of Health & Ageing, National Health & Medical Research Council. Nutrient Reference Values for Australia & New Zealand - Including Recommended Dietary Intakes. 2006

20. Superior Health Council of Belgium. Recommendations and claims made on omega-3-fatty Acids (SHC 7945). 2005

21. AFFSA (France). Avis de l'Agence française de sécurité sanitaire des aliments relatif à l'actualisation des apports nutritionnels conseillés pour les acides gras. March 1, 2010. http://www.afssa.fr/cgi-bin/countdocs.cgi?Documents/NUT2006sa0359EN.pdf. Accessed March 25, 2010.

22. Simopolous, A. Summary of the NATO Advanced Research Workshop on Dietary w3 and w6 Fatty Acids: Biological Effects and Nutritional Essentiality. Journal of Nutrition, 1989; 521-528.

23. American Dietetic Association and Dieticians of Canada. Position of the American Dietetic Association and Dietitians of Canada: Dietary Fatty Acids. Journal of the American Dietetic Association, 2007; 1599-1611.

24. World Gastroenterology Organisation. 10 nutritional recommendations to improve Digestive Health. Published May 29, 2008. http://www.worldgastroenterology.org/assets/downloads/pdf/wdhd/2008/events/wdhd08_cartel_10_global_nutrition.pdf. Accessed August 3, 2008.

25. EFSA Panel on Dietetic Products, Nutrition, and Allergies (NDA); Scientific Opinion on Dietary Reference Values for fats, including saturated fatty acids, polyunsaturated fatty acids, monounsaturated fatty acids, trans fatty acids, and cholesterol. EFSA Journal 2010; 8(3):1461. [107 pp.]. doi:10.2903/j.efsa.2010.1461. Available online: www.efsa.europa.eu

26. "Japanese Nutritional Requirement - Dietary Reference Intakes ? Policy-Making Committee" (Chairperson ? Mr. Heizo Tanaka, Former Board Chairman of National Institute of Health and Nutrition). Announced October,2004 and valid from 2005 to 2010 (For 5 years)

27. Health Council of the Netherlands, 2006. Guidelines for a healthy diet 2006. The Hague: publication # 2006/21E. Available from: http://www.gr.nl/pdf.php?ID=1481&p=1

28. National Health and Medicines Research Council. Nutrient Reference Values for Australia and New Zealand. Commonwealth of Australia, 2006. Accessed at http://www.nhmrc.gov.au/publications/synopses/_files/n35.pdf

29. Koletzko B, Lien E, Agostoni C, Böhles H, Campoy C, Cetin I, Decsi T, Dudenhausen JW, Dupont C, Forsyth S, Hoesli I, Holzgreve W, Lapillonne A, Putet G, Secher NJ, Symonds M, Szajewska H, Willatts P, Uauy R; World Association of Perinatal Medicine Dietary Guidelines Working Group. The roles of long-chain polyunsaturated fatty acids in pregnancy, lactation and infancy: review of current knowledge and consensus recommendations. J Perinat Med. 2008; 36(1):5-14.

30. Wang C, Chung M, Lichtenstein A, Balk E, Kupelnick B, DeVine D, Lawrence A, Lau J. Effects of Omega-3 Fatty Acids on Cardiovascular Disease. Evidence Report/Technology Assessment No. 94 (Prepared by Tufts-New England Medical Center Evidence-based Practice Center, under Contract No. 290-02-0022). AHRQ Publication No. 04-E009-2. Rockville, MD: Agency for Healthcare Research and Quality. March 2004.

31. Koletzko B, Cetin I, Brenna J. Consensus statement- Dietary fat intakes for pregnant and lactating women. Brit J Nutr. 2007; 98:873-877.

32. March of Dimes. Omega-3 Fatty Acids During Pregnancy. March of Dimes Web Site, 2009. Accessed June 17, 2009 at http://www.marchofdimes.com/pnhec/159_55030.asp.

33. D-A-CH, 2008 Deutsche Gesellschaft für Ernährung, Österreichische Gesellschaft für Ernährung, Schweizerische Gesellschaft für Ernährungsforschung, Schweizerische Vereinigung für Ernährung: Referenzwerte für die Nährstoffzufuhr, Umschau/Braus Verlag, Frankfurt.

34. Forbes-Ewan, C. Australian Defence Force Nutritional Requirements in the 21st Century (Version 1). Human Protection and Performance Division, Defence Science and Technology Organisation, 2009.

Dietary Recommendations for Omega-3 Fatty Acids

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